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尿激酶抑制剂筛选试剂盒

Urokinase Inhibitor Screening Kit
产品编号:3258126
产品类别:试剂盒
纯度规格:Sufficient for 100 Fluorometric tests
包装规格:1 KIT
市场价:6880元
优惠价:立即咨询

尿激酶抑制剂筛选试剂盒

Urokinase Inhibitor Screening Kit

uPA Inhibitor Screening Kit

Urokinase-type Plasminogen Activator Inhibitor Screening Kit

Plasminogen Activator Inhibitor Screening Kit

纤溶酶原激活剂抑制剂筛选试剂盒

uPA抑制剂筛选试剂盒

激酶型纤溶酶原激活剂抑制剂筛选试剂盒

基本信息
NACRES
NA.25
General description【一般描述】
Urokinase (Urokinase-type plasminogen activator, uPA, EC 3.4.21.73) is a serine protease involved in the degradation of extracellular matrix components. It cleaves the Arg-Val bond in plasminogen and converts it to plasmin. The activity of uPA is important in tumor cell proliferation and migration. Polymorphisms in uPA gene are reportedly associated with Alzheimer′s disease.
Principle【原理】
The Urokinase Inhibitor Screening Kit is a rapid, simple and sensitive assay that is suitable for the screening of Urokinase inhibitors. Urokinase activity is measured by cleaving a synthetic 7-amino-4-trifluoromethylcoumarin (AFC)-based substrate to yield AFC, a fluorescent product (λex = 350/ λem = 450 nm), proportional to the enzymatic activity present.
Components【组分】
组份不可单独销售
Urokinase Assay Buffer
Urokinase Substrate
Human Urokinase
Urokinase Inhibitor; 10 mM GGACK Dihydrochloride
产品性质
Detection Method
fluorometric
storage temp.【储存温度】
−20℃
Gene Information
human ... PLAU(5328)
mouse ... PLAU(18792)
rat ... PLAU(25619)
suitability【适用性】
适于筛选尿激酶抑制剂。
安全信息
Pictograms【象形图】
GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H334
Precautionary Statements
P261 - P284 - P501
Hazard Classifications【危险分类】
Resp. Sens. 1
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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