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Tetrazine-PEG5-NHS ester
产品别名
1682653-80-0
Tetrazine-PEG5-NHS ester
Tz-PEG5-NHS
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H36N6O10 |
| Molecular weight | 604.61 |
| MDL number | MFCD28505547 |
| NACRES | NA.22 |
| General description【一般描述】 | Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm. |
| Application【应用】 | Tetrazine-PEG5-NHS ester (Tz-PEG5-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | powder or crystals |
| reaction suitability | reaction type: click chemistry |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
