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InSolution Akt 抑制剂 V，曲西立滨-CAS 35943-35-2-Calbiochem
InSolution Akt Inhibitor V, Triciribine-CAS 35943-35-2-Calbiochem
| 产品编号： | 4157506 |
| 规格： | The InSolution |
| CAS NO： | 35943-35-2 |
| 包装规格： | 2 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4157506 | 2 MG | 4330 |
产品别名
35943-35-2
InSolution
InSolution Akt Inhibitor V, Triciribine-CAS 35943-35-2-Calbiochem
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H16N6O4 |
| Molecular weight | 320.30 |
| General description【一般描述】 | A cell-permeable and reversible tricyclic nucleoside that selectively inhibits the cellular phosphorylation/activation of Akt1/2/3 by targeting an Akt effector molecule other than PI 3-K or PDK. Exhibits little effect towards cellular signaling pathways mediated by PKC, PKA, SGK, Stat3, p38, ERK1/2, or JNK. Shown to preferentially induce apoptosis and growth arrest in cancer cells with aberrant Akt activity both in vitro (≥60% in cell proliferation at 20 µM) and in vivo (≥80% inhibition in tumor growth in mice at 1 mg/kg/day, i.p.). |
| Warning【警告】 | Toxicity: Irritant (B) |
| Physical form【外形】 | A 2 mg/312 µl solution of Akt Inhibitor V, Triciribine (Cat. No. 124012) in DMSO. |
| Reconstitution【重悬】 | Following intitial thaw, aliquot and freeze (-70°C). |
| Other Notes【其他说明】 | Karst, A., et al. 2006. Cancer Res.66, 9225. Yang, L., et al. 2004. Cancer Res.64, 4394. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles desiccated (hygroscopic) protect from light |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −70℃ |
| InChI | 1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1 |
| InChI key | HOGVTUZUJGHKPL-HTVVRFAVSA-N |
| packaging【包装】 | 2 mg in Glass bottle Packaged under inert gas |
