Galanthamine, Hydrobromide-CAS 69353-21-5-Calbiochem

C₁₇H₂₁NO₃ · xHBr

287.35 (free base basis)

A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Cholinesterase antagonist. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats.

Primary Target
Acetylcholinesterase
Product competes with ATP.
Cell permeable: no
Reversible: yes

Toxicity: Toxic (F)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Pilger, C., et al. 2001. J. Mol. Graph. Model19, 288.
Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
Southan, G.J., et al. 1996. Br. J. Pharmacol.117, 619.
Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.
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CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (HPLC)

solid

Calbiochem^®

OK to freeze
desiccated

white

ethanol: 1 mg/mL
water: 1 mg/mL
DMSO: 5 mg/mL

ambient

2-8℃

1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

QORVDGQLPPAFRS-XPSHAMGMSA-N

GHS06

Danger

H301

P264 - P270 - P301 + P310 - P405 - P501

Acute Tox. 3 Oral

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK 3