FeTPPS-Calbiochem

C₄₄H₂₈ClFeN₄O₁₂S₄

1024.27

A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC₅₀ = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Provides cytoprotection against peroxynitrite (EC₅₀ = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.

EC50 = 5 µM for cytoprotection against peroxynitrite
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Selective peroxynitrite scavenger

Toxicity: Standard Handling (A)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.

Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci.914, 157.
Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (TLC)

solid

Calbiochem^®

OK to freeze
desiccated (hygroscopic)
protect from light

dark brown

water: soluble

ambient

2-8℃

25 mg in Plastic ampoule
Packaged under inert gas

11 - Combustible Solids

WGK 1