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c-MET, GST-Fusion, Human, Recombinant, S. frugiperda
产品编号: | 4155461 |
规格: | c-MET, GST-Fusion, Human, Recombinant (aa 956-1390) fused at the N-terminus to a GST-His6-thrombin cleavage site and expressed in S. frugiperda. c-Met is a receptor tyrosine kinase activated by HGF. |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
c-MET, GST-Fusion, Human, Recombinant, S. frugiperda
Hepatocyte growth factor receptor tyrosine kinase
产品性质
Quality Level【质量水平】 | 100 |
recombinant【重组】 | expressed in baculovirus infected Sf21 cells |
form【形式】 | liquid |
Specific Activity | ≥30 units/mg protein |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −70℃ |
packaging【包装】 | 10 μg in Plastic ampoule Please refer to vial label for lot-specific concentration. |
基本信息
General description【一般描述】 | Recombinant, human c-MET (amino acids 956-1390) (Genebank entry NM_000245) fused at the N-terminus to a GST-His6-thrombin cleavage site sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. c-Met is a receptor tyrosine kinase activated by hepatocyte growth factor (HGF)/scatter factor (SF). c-MET is a plasminogen-like protein thought to be a humoral mediator of liver regeneration. Recombinant, human MET (amino acids 956-1390) (Genebank entry NM_000245) fused at the N-terminus to a GST-His6-thrombin cleavage site sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. c-Met is a receptor tyrosine kinase activated by hepatocyte growth factor (HGF)/scatter factor (SF). MET is a plasminogen-like protein thought to be a humoral mediator of liver regeneration. |
Warning【警告】 | Toxicity: Standard Handling (A) |
Unit Definition【单位定义】 | One unit is defined as the amount of enzyme required to transfer 1 nmol phosphate to Poly(Ala, Glu, Lys, Tyr)6:2:5:1 per min at 30°C, using variable concentrations of ATP (0.1-1.48 µM). |
Physical form【外形】 | In 100 mM NaCl, 50 mM Tris-HCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol, pH 8.0. |
Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-70°C). |
Other Notes【其他说明】 | Palka, H.L., et al. 2003. J. Biol. Chem.278, 5278. Vadnais, J., et al. 2002. J. Biol. Chem.277, 48342. Crostella, L., et al. 2001. Oncogene20, 3735. Guiton, M., et al. 1994. J. Biol. Chem269, 30370. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |