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Anti-UVRAG Antibody

产品编号:4155061
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4155061100 μG6190
产品别名

Anti-UVRAG Antibody

UV radiation resistance-associated gene protein, p63

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
UV irradiation resistance-associated gene (UVRAG) is an essential component of the Beclin1-PI(3)KC3 lipid kinase complex which functions as an important signaling checkpoint for autophagy and tumor-cell growth. More specifically, UVRAG seems to work as a multivalent trafficking effector that controls autophagosome formation and maturation, and also controls the engaging of the fusion apparatus to the endosome. UVRAG may be a promising target for cancer therapies.
Specificity【特异性】
This antibody recognizes the C-terminus of UVRAG.
Immunogen【免疫原】
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human UVRAG.
Application【应用】
Research Sub Category
Apoptosis - Additional
Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated UVRAG from 500 µg from Raji cell lysate.

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected UVRAG in NIH/3T3 and A431 cells.
Research Category
Apoptosis & Cancer
Anti-UVRAG Antibody is an antibody against UVRAG for use in WB, IC & IP.
Quality【质量】
Evaluated by Western Blot in Raji cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected UVRAG in 10 µg of Raji cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
Analysis Note【分析说明】
Control
Raji cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
mouse, human, rat
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_003360
UniProt accession no.【UniProt登记号】
Q9P2Y5
shipped in【运输】
wet ice
Gene Information
human ... UVRAG(7405)
产品说明
Target description【目标描述】
~78 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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