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Anti-Uncoupling Protein 3 Antibody
产品别名
Anti-Uncoupling Protein 3 Antibody
UCP3
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Human UCP3 long form (UCP3L) is a 312 aa mitochondrial uncoupling protein. It is only 57% and 73% homologous with human UCP1 and UCP2 respectively. Like other UCPs, UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and is only 275 aa long. UCP3 has preferential expression in muscle and it is unaffected by cold acclimation. |
Specificity【特异性】 | Uncoupling Protein 3 (UCP3), human. It is expected that the antibody will recognize both the long and short forms (30-33 kDa & 24-27 kDa) however splice variants are expected and precise reactivity profile has yet to be determined. Human UCP3 long form (UCP3L) is a 312 aa mitochondrial uncoupling protein (Boss et al. 1997; Vidal-Puig et al. 1997). It is only 57% and 73% homologous with human UCP1 and UCP2 respectively. Like other UCPs, UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and is only 275 aa long (Vidal-Puig et al. 1997). UCP3 has preferential expression in muscle and it is unaffected by cold acclimation. |
Immunogen【免疫原】 | 14 amino acid peptide sequence (designated UCP32) mapping near the C-terminus of human UCP3 (Boss et al. 1997). The UCP32 peptide has no significant homology with UCP1 or UCP2. |
Application【应用】 | Research Sub Category Ion & Transport Channels Research Category Metabolism Western Blotting: 1-10 μg/mL using Chemiluminescence technique. Immunohistochemistry: 2-20 μg/mL on formaldehyde fixed tissue. ELISA: (1:10,000-1:100,000 using 50-100 ng UCP32 control peptide/well). Optimal working dilutions must be determined by end user. Anti-Uncoupling Protein 3 Antibody is an antibody against Uncoupling Protein 3 for use in ELISA, IH & WB. |
Physical form【外形】 | ImmunoAffinity Purified Affinity Purified immunoglobulin. Liquid in PBS with 0.1% BSA. |
Analysis Note【分析说明】 | Control Muscle tissue, Blocking peptide for UCP3 is available (Catalogue No. AG769). |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | rat, human |
manufacturer/tradename | Chemicon® |
technique(s) | ELISA: suitable immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_003356.2 NM_022803.1 |
UniProt accession no.【UniProt登记号】 | P55916 |
shipped in【运输】 | dry ice |
产品说明
Target description【目标描述】 | 30-33 kDa & 24-27 kDa |
Storage and Stability【储存及稳定性】 | Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |