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Anti-Tbr1 Antibody

产品编号:4155001
规格:from chicken, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4155001100 μG6690
产品别名

Anti-Tbr1 Antibody

T-box, brain, 1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
Specificity【特异性】
This antibody recognizes Tbr1.
Immunogen【免疫原】
Epitope: Internal
KLH-conjugated linear peptide corresponding to mouse Tbr1.
Application【应用】
Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected Tbr1 in mouse frontal cortex tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Anti-Tbr1 Antibody is an antibody against Tbr1 for use in WB, IH.
Quality【质量】
Evaluated by Western Blot in human fetal brain tissue lysate.

Western Blot Analysis: 0.025 µg/ml of this antibody detected Tbr1 on 10 µg of human fetal brain tissue lysate.
Physical form【外形】
Affinity purified
Purified chicken polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Analysis Note【分析说明】
Control
Human fetal brain tissue lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
chicken
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
mouse, human, rat
species reactivity (predicted by homology)
opossum (based on 100% sequence homology), bovine (based on 100% sequence homology), horse (based on 100% sequence homology), canine (based on 100% sequence homology), pig (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_033348
UniProt accession no.【UniProt登记号】
Q64336
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~ 68 kDa is observed; however, UniProtKB/Swiss-Prot entry Q64336 (TBR1_MOUSE) lists a mass of 73.941 kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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