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Anti-Superoxide Dismutase 1 Antibody, aa 25-37
产品别名
Anti-Superoxide Dismutase 1 Antibody, aa 25-37
SOD1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Mutations in the copper/ zinc superoxide dismutase (SOD1) gene are associated with 15- 20% of the familial forms of motoneuron disease. This 153 amino acid metalloenzyme is expressed in virtually all cells of all organisms above bacteria and is highly conserved across species, although some minor variations do occur. The incorporation of the mutated form of the SOD1 human gene into a transgenic mouse leads to the onset of the disease that closely resembles the human condition. These animals become weak at about 2-4 months of age and rapidly lose function, which results in death 4- 6 weeks later. |
Specificity【特异性】 | Superoxide Dismutase 1 (SOD1), human specific. |
Immunogen【免疫原】 | Synthetic peptide corresponding to amino acids 25-37 of human SOD1. Epitope: aa 25-37 |
Application【应用】 | Anti-Superoxide Dismutase 1 Antibody, aa 25-37 detects level of Superoxide Dismutase 1 & has been published & validated for use in WB. Western blotting: 1:500 Optimal working dilutions must be determined by end user. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | serum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human |
should not react with | mouse |
manufacturer/tradename | Chemicon® |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_000454.4 |
UniProt accession no.【UniProt登记号】 | P00441 |
shipped in【运输】 | dry ice |
Gene Information | human ... SOD1(6647) |
产品说明
Storage and Stability【储存及稳定性】 | Maintain lyophilized material at -70°C (dry) for up to 12 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability. |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |