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Anti-Sox10 Antibody

产品编号:4154953
规格:Chemicon®, from rabbit
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4154953100 μG6690
基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Sox 10 is part of a family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Sox 10 is expressed in multipotent neural crest stem cells, and its expression is downregulated upon their differentiation. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
Specificity【特异性】
Sox10. The immunogen sequence is 70% conserved with Sox8 and Sox9 and therefore the antibody may show cross reactivity to these proteins.
Immunogen【免疫原】
Synthetic peptide from Sox10.
Application【应用】
Research Category
Neuroscience
Western blot: 0.1-0.5 μg/mL using ECL on fetal mouse brain tissue lysate. The antibody reacts with proteins of ~60 kDa. An additional band of ~120 kDa may also be seen depending on sample used.

Optimal working dilutions must be determined by the end user.
Anti-Sox10 Antibody detects level of Sox10 & has been published & validated for use in WB.
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers
Linkage【联系】
Replaces: AB5774
Physical form【外形】
Affinity purified immunoglobulin. Liquid.
Legal Information【法律信息】
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity purified immunoglobulin
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
mouse
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NM_006941.3
UniProt accession no.【UniProt登记号】
P56693
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
Approx. 55 kDa
Storage and Stability【储存及稳定性】
Maintain at +2-8°C in undiluted aliquots for up to 6 months after date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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