您的位置:首页 > 产品中心 > Anti-Orexin Antibody, Prepro
Anti-Orexin Antibody, Prepro
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
Specificity【特异性】 | Mouse Prepro-Orexin. Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (Sakurai et al. 1998). Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis (Sakurai et al. 1998). These neuropeptides bind and activate two closely related Orexin receptors--G protein coupled receptors (GPCRs) OX1R and OX2R. |
Immunogen【免疫原】 | A 17 mer peptide (designated PPOXA11-A) mapping near the C-terminus of mouse prepro-Orexin. |
Application【应用】 | Research Sub Category CNS Control of Metabolism Circadian Rhythm & Sleep Research Category Neuroscience Anti-Orexin Antibody, Prepro is an antibody against Orexin for use in ELISA, IH & WB. Western blot: 1-10 μg/mL using Chemiluminescence technique ELISA: 1:10,000 - 100,000 Immunohistochemistry: 2-20 μg/mL. Optimal working dilutions must be determined by end user. |
Physical form【外形】 | Liquid in PBS with 0.1% BSA. |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human, mouse, rat |
manufacturer/tradename | Chemicon® |
technique(s) | ELISA: suitable immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_001524.1 |
UniProt accession no.【UniProt登记号】 | O43612 |
shipped in【运输】 | dry ice |
Gene Information | human ... PPOX(5498) |
产品说明
Storage and Stability【储存及稳定性】 | Can be refrigerated at 2-8°C in undiluted aliquots for short term use. Maintain frozen at -20°C in undiluted aliquots for up to 12 months. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |