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Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4
产品别名
Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4
poliovirus receptor-related 3, poliovirus receptor-related protein 3, nectin 3, nectin-3, Nectin-3, CD113 antigen
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Nectin-3, also known as Poliovirus receptor-related protein 3 (PVRL3) and PRR3, is thought to work with cadherin to form cell-cell adherens junctions. It is a transmembrane protein that is commonly found in the testis and in placental tissue. Nectin-3 colocalizes with CD155, the cognate receptor for poliovirus, to cell-cell junctions. Nectin-3′s involvement in down-regulation PVR from the cell surface leads to a reduction in cell motility and proliferation. |
| Immunogen【免疫原】 | Full length recombinant protein corresponding to human Nectin-3. |
| Application【应用】 | Research Category Cell Structure Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4 detects level of Nectin-3/PVRL3 (CD113) & has been published & validated for use in FC. Research Sub Category ECM Proteins |
| Quality【质量】 | Evaluated by Flow Cytometry in U251 cells. Flow Cytometry Analysis: 0.1 µg of this antibody detected Nectin-3 in U251 cells. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control U251 cells |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | N3.12.4, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_056295 |
| UniProt accession no.【UniProt登记号】 | Q9NQS3 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 61 kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
