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Anti-mGCM1 Antibody
| 产品编号： | 4154614 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-mGCM1 Antibody
GCM motif protein 1, Glial cells missing homolog 1, chorion-specific transcription factor GCMa, glial cells missing homolog a
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | GCM1 is a DNA binding protein with a GCM motif (glial cell missing motif) that is a key transcription factor for determining the fate of stem cells within the nervous system, in addition to being critical for placental development. This protein binds to the GCM motif (A/G)CCCGCAT, a novel sequence among known targets of DNA binding proteins. The N-terminal DNA-binding domain confers the unique DNA binding activity of this protein. Current studies indicate that the introduction of the mouse GCM1 gene in cultured cells from embryonic brains resulted in the induction of an astrocyte lineage. |
| Specificity【特异性】 | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from the C-terminal region mouse GCM1. Comparison of sequence homology suggests that this antibody will also react in mouse and rat; however, reactivity to other species has not been tested. |
| Immunogen【免疫原】 | Synthetic GCM1 peptide, a.a. 401-418. Epitope: C-terminus |
| Application【应用】 | Research Category Stem Cell Research Research Sub Category Neural Stem Cells This Anti-mGCM1 Antibody is validated for use in WB for the detection of mGCM1. |
| Quality【质量】 | Routinely evaluated by western blot on HEK-293 lysates. Western Blotting: Recommended working dilutions are 1:1000 – 1:2500. |
| Physical form【外形】 | Purified rabbit polyclonal antibody in buffer containing PBS with 0.09% sodium azide. Peptide affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| input | sample type pancreatic stem cell(s) sample type neural stem cell(s) |
| UniProt accession no.【UniProt登记号】 | P70348 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 50 kDa |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
