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Anti-ISL-1 Antibody, clone 16E8.1
产品别名
Anti-ISL-1 Antibody, clone 16E8.1
Insulin gene enhancer protein ISL-1, Islet-1, ISL1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Islet-1 (ISL-1) is a transcription factor that plays an important role in the embryogenesis of pancreatic islets of Langerhans. It is expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. In mouse embryos, a deficiency of this gene fail to undergo neural tube motor neuron differentiation. More recently it has been identified as a marker for a cardiac progenitor cell lineage that is capable of differentiating into all 3 major heart cell types: cardiomyocytes, smooth muscle and endothelial cell lineages. |
| Immunogen【免疫原】 | GST-tagged linear peptide corresponding to Human ISL-1. |
| Application【应用】 | Evaluated by Immunohistochemistry in both human cerebellum and rat hippocampal tissue. Immunohistochemsitry Analysis: A 1:1000 dilution of this antibody detected ISL-1 in both human cerebellum and rat hippocampal tissue. This Anti-ISL-1 Antibody, clone 16E8.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of ISL-1. Research Sub Category Pluripotent & Early Differentiation Research Category Stem Cell Research |
| Quality【质量】 | Evaluated by Western Blot in a K562 cell lysate. Western Blot Analysis: A 1μg/ml (1:1000) dilution of this antibody detected ISL-1 in a K562 cell lysate. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG2bκ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 16E8.1, monoclonal |
| species reactivity | human, rat |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| isotype【同位素/亚型】 | IgG2bκ |
| NCBI accession no.【NCBI登记号】 | NP_002193 |
| UniProt accession no.【UniProt登记号】 | P61371 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... ISL1(3670) |
产品说明
| Target description【目标描述】 | ~ 40 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
