您的位置:首页 > 产品中心 > Anti-CEACAM1 Antibody, clone 4D1/C2
Anti-CEACAM1 Antibody, clone 4D1/C2
产品别名
Anti-CEACAM1 Antibody, clone 4D1/C2
Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1, BGP-1, CD66a
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is thought to be a member of the immunoglobulin superfamily and is known as an epithelial tumor suppressor and an angiogenic growth factor. It has also been linked to the actin-based cytoskeleton. CEACAM1 is also known as a cellular receptor for a number of human mucosa pathogenic bacteria. The loss of activity of CEACAM1 has been related to the development of colorectal cancer. |
Immunogen【免疫原】 | Recombinant protein corresponding to human CEACAM1. Epitope: Unknown |
Application【应用】 | Research Category Cell Structure Immunohistochemistry Analysis: A representative lot was used by an independent laboratory to detect CEACAM1 in non-small-cell lung cancer (Dango, S., et al. (2008). Lung Cancer. 60:426-433). Western Blot Analysis: A representative lot was used by an independent laboratory to detect CEACAM1 in human granulocyte lysate (Bogoevska, V. et al., (2006). Glycobiology. 16(3): 197–209). Flow Cytometry Analysis: A representative lot was used by an independent laboratory to detect CEACAM1 in human granulocytes by FACS analysis (Bogoevska, V. et al., (2006). Glycobiology. 16(3): 197–209). Detect CEACAM1 using this Anti-CEACAM1 Antibody, clone 4D1/C2 validated for use in WB, IH. Research Sub Category Adhesion (CAMs) |
Quality【质量】 | Evaluated by Western Blot in HepG2 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected CEACAM1 in 10 µg of HepG2 cell lysate. |
Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
Analysis Note【分析说明】 | Control HepG2 cell lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | 4D1/C2, monoclonal |
species reactivity | human |
technique(s) | ELISA: suitable flow cytometry: suitable immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_001020083 |
UniProt accession no.【UniProt登记号】 | P13688 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~150 kDa observed. Bands are usually observed at ~120-160 kDa, resulting from different glycosylations (Lauke, H., et al. (2004). Mol. Hum. Reprod. 10(4):247-252). |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |