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Anti-Aggrecan Antibody, clone 1-C-6
产品别名
Anti-Aggrecan Antibody, clone 1-C-6
Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Aggregating chondroitin sulfate proteoglycan or aggrecan, is one of the most studied proteoglycans. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular cartilage and compromises 10% of its dry weight. |
| Immunogen【免疫原】 | Reduced and alkylated Aggrecan isolated from Swarm Rat Chondrosarcoma |
| Application【应用】 | This Anti-Aggrecan Antibody, clone 1-C-6 is validated for use in IH, WB for the detection of Aggrecan. Western Blot Analysis: 1 µg/mL from a representative lot detected Aggrecan on 10 µg of A1D4 protein fraction from Bovine tissue. |
| Quality【质量】 | Evaluated by Immunohistochemistry in normal mouse cartilage and normal rat cartilage tissues. Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Aggrecan in normal mouse cartilage and normal rat cartilage tissues. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Analysis Note【分析说明】 | Control Normal mouse cartilage and normal rat cartilage tissues |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 1-C-6, monoclonal |
| species reactivity | bovine, rat, mouse |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_071526 |
| UniProt accession no.【UniProt登记号】 | P07897 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | Various |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
