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5-Nitro-2-(3-phenylpropylamino)benzoic Acid-CAS 107254-86-4-Calbiochem

产品编号:4153424
规格:Potent Cl- channel blocker (IC50 = 100 nM-100 μM), depending on channel subtype and assay method.
CAS NO:107254-86-4
包装规格:10 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
415342410 MG1710
产品别名

107254-86-4

5-Nitro-2-(3-phenylpropylamino)benzoic Acid-CAS 107254-86-4-Calbiochem

NPPB, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II, ANO Blocker II, Anoctamin Blocker II

基本信息
Empirical Formula【经验(实验)分子式】
C16H16N2O4
Molecular weight
300.31
MDL number
MFCD00153851
General description【一般描述】
Potent Cl channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
Potent Cl- channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
Biochem/physiol Actions【生化/生理作用】
Product does not compete with ATP.
Reversible: no
Primary Target
Cl⁻ channel blocker
Target IC50: 100 nM-100 µM as Cl-channel blocker
Cell permeable: no
Warning【警告】
Toxicity: Standard Handling (A)
Other Notes【其他说明】
Illek, B., et al. 1992. Am. J. Physiol.263, C644.
Kirk, K., et al. 1992. J. Biol. Chem.267, 23475.
Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun.163, 398.
Wangermann, P., et al. 1986. Pflugers Arch.407, S128.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
color【颜色】
yellow
solubility【溶解性】
DMSO: 5 mg/mL
warm ethanol: soluble
shipped in【运输】
ambient
storage temp.【储存温度】
10-30℃
InChI
1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
InChI key
WBSMIPAMAXNXFS-UHFFFAOYSA-N
packaging【包装】
10 mg in Plastic ampoule
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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