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Thiophosphoro alkyne dichloridate
产品别名
21300-59-4
Thiophosphoro alkyne dichloridate
Propargyl thiophosphorodichloridate
O-(Prop-2-yn-1-yl) phosphorodichloridothioate
Chemoselective histidine labeling reagent
Phosphorodichloridothioate 2-propyn-1-ol
Thiophosphorus electrophile
TPAC
Thiophosphorodichloridate reagent
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C3H3Cl2OPS |
| Molecular weight | 189.00 |
| Application【应用】 | Thiophosphoro alkyne dichloridate (TPAC) is a histidine labeling reagent developed by the Chang lab that mimics native post-translational His phosphorylation. The alkyne allows for subsequent reactions or addition of payloads by copper-assisted alkyne-azide cycloaddition (CuAAC) chemistry. TPAC was also demonstrated to covalently modify His-tags, and by clicking on polyarginine tags, enabled protein delivery into live cells. |
| Other Notes【其他说明】 | Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | liquid |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| Flash Point(F)【闪点(F)】 | 175.8 °F |
| Flash Point(C)【闪点(C)】 | 79.9 ℃ |
