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PARP Inhibitor I, 3-ABA-CAS 3544-24-9-Calbiochem

产品编号:4146193
规格:The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
CAS NO:3544-24-9
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4146193100 MG862
产品别名

3544-24-9

PARP Inhibitor I, 3-ABA-CAS 3544-24-9-Calbiochem

3-Aminobenzamide

基本信息
Empirical Formula【经验(实验)分子式】
C7H8N2O
Molecular weight
136.15
MDL number
MFCD00007989
General description【一般描述】
A cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
Biochem/physiol Actions【生化/生理作用】
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
PARP
Warning【警告】
Toxicity: Irritant (B)
Reconstitution【重悬】
Following reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
Other Notes【其他说明】
Tiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
Monti, D., et al. 1994. Biochem. Biophys. Res. Commun.199, 525.
Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun.179, 1225.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥99% (GC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
color【颜色】
white
solubility【溶解性】
ethanol: 1 mg/mL
water: 1 mg/mL
DMSO: 5 mg/mL
shipped in【运输】
ambient
storage temp.【储存温度】
10-30℃
InChI
1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)
InChI key
GSCPDZHWVNUUFI-UHFFFAOYSA-N
packaging【包装】
100 mg in Plastic ampoule
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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