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Isoproterenol, Hydrochloride-CAS 51-30-9-Calbiochem
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4145249 | 100 MG | 778 |
产品别名
51-30-9
Isoproterenol, Hydrochloride-CAS 51-30-9-Calbiochem
基本信息
Empirical Formula【经验(实验)分子式】 | C11H17NO3 · xHCl |
Molecular weight | 211.26 (free base basis) |
MDL number | MFCD00012603 |
General description【一般描述】 | Phenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process. |
Biochem/physiol Actions【生化/生理作用】 | Primary Target β-adrenergic agonist Product does not compete with ATP. Reversible: no Cell permeable: no |
Warning【警告】 | Toxicity: Irritant (B) |
Reconstitution【重悬】 | Unstable in solution; reconstitute just prior to use. |
Other Notes【其他说明】 | Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem.275, 25342. Carmena, M.J., et al. 1997. Prostate 33, 46. Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584. Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300. Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27. Yashiro, K., et al. 1994. J. Biochem.115, 1040. Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260. von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763. Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥99% (TLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | white to off-white white |
solubility【溶解性】 | ethanol: soluble water: soluble |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 10-30℃ |
InChI | 1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H |
InChI key | IROWCYIEJAOFOW-UHFFFAOYSA-N |
packaging【包装】 | 100 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 2 |