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InSolution SU6656-Calbiochem

产品编号:4145204
包装规格:500 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4145204500 μG2150
基本信息
Empirical Formula【经验(实验)分子式】
C19H21N3O3S
Molecular weight
371.45
General description【一般描述】
A potent inhibitor of Src-family protein tyrosine kinases. Inhibits Src (IC50 = 280 nM) as well as closely related kinases Fyn (IC50 = 170 nM), Yes (IC50 = 20 nM) and Lyn (IC50 = 130 nM). The inhibition is competitive with respect to ATP. Has only a trivial effect on Lck (IC50 = 6.88 µM). Does not affect the activity of PDGF-β receptor kinase (IC50 >10 µM) and IGF-1 receptor kinase (IC50 gt;20 µM).
Biochem/physiol Actions【生化/生理作用】
Cell permeable: yes
Target IC50: 280 nM inhibiting Src
Product competes with ATP.
Reversible: yes
Warning【警告】
Toxicity: Irritant (B)
Physical form【外形】
A 10 mM (500 µg/135 µl) solution of SU6656 (Cat. No. 572635) in DMSO.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥95% (HPLC)
form【形式】
liquid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
desiccated (hygroscopic)
protect from light
shipped in【运输】
wet ice
storage temp.【储存温度】
2-8℃
packaging【包装】
500 μg in Plastic ampoule
Packaged under inert gas
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)【闪点(F)】
188.6 °F - (Dimethylsulfoxide)
Flash Point(C)【闪点(C)】
87 ℃ - (Dimethylsulfoxide)
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