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InSolution Caspase-8 Inhibitor II-Calbiochem

产品编号:4145190
规格:The InSolution Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
包装规格:250 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4145190250 μG2300
产品别名

InSolution Caspase-8 Inhibitor II-Calbiochem

Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK

基本信息
Empirical Formula【经验(实验)分子式】
C30H43FN4O11
Molecular weight
654.68
General description【一般描述】
A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.
Biochem/physiol Actions【生化/生理作用】
Primary Target
caspase-8
Product does not compete with ATP.
Cell permeable: yes
Reversible: no
Warning【警告】
Toxicity: Irritant (B)
Sequence【序列】
Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
Physical form【外形】
A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
Reconstitution【重悬】
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note【分析说明】
single spot by TLC
Other Notes【其他说明】
Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
form【形式】
liquid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
desiccated (hygroscopic)
protect from light
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
packaging【包装】
250 μg in Glass bottle
Packaged under inert gas
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)【闪点(F)】
188.6 °F - (refers to pure substance)
Flash Point(C)【闪点(C)】
87 ℃ - (refers to pure substance)
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