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InSolution Caspase-8 Inhibitor II-Calbiochem
产品编号: | 4145190 |
规格: | The InSolution |
包装规格: | 250 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
InSolution Caspase-8 Inhibitor II-Calbiochem
Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
基本信息
Empirical Formula【经验(实验)分子式】 | C30H43FN4O11 |
Molecular weight | 654.68 |
General description【一般描述】 | A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B. |
Biochem/physiol Actions【生化/生理作用】 | Primary Target caspase-8 Product does not compete with ATP. Cell permeable: yes Reversible: no |
Warning【警告】 | Toxicity: Irritant (B) |
Sequence【序列】 | Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F* |
Physical form【外形】 | A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. |
Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). |
Analysis Note【分析说明】 | single spot by TLC |
Other Notes【其他说明】 | Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345. Sweeney, E.A., et al. 1998. FEBS Lett.425, 61. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
form【形式】 | liquid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 250 μg in Glass bottle Packaged under inert gas |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |
Flash Point(F)【闪点(F)】 | 188.6 °F - (refers to pure substance) |
Flash Point(C)【闪点(C)】 | 87 ℃ - (refers to pure substance) |