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Histone Deacetylase 6, GST-Fusion, Human Recombinant, S. frugiperda
产品编号: | 4145148 |
规格: | Histone Deacetylase 6, GST-Fusion, Human Recombinant, S. frugiperda, is a full-length HDAC6 fused to GST at the N-terminus. Useful in the study of HDAC6 regulation and for inhibitor screening. |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Histone Deacetylase 6, GST-Fusion, Human Recombinant, S. frugiperda
HDAC6, Human, Recombinant
产品性质
recombinant【重组】 | expressed in insect cells (S. frugiperda) |
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥80% (SDS-PAGE) |
form【形式】 | liquid |
Specific Activity | ≥50 units/μg protein |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −70℃ |
packaging【包装】 | 50 μg in Plastic ampoule Please refer to vial label for lot-specific concentration. |
基本信息
General description【一般描述】 | Full length, recombinant, human histone deacetylase 6 (HDAC6) fused to GST at the N-terminus and expressed in S. frugiperda insect cells using a baculovirus expression system. Actively maintained in the cytoplasm, HDAC6 is uniquely dependent on its ubiquitin-binding domain and functions at the nexus between two cellular signaling systems, involving protein acetylation and ubiquitination. The active deacetylase is useful in the study of HDAC6 regulation and for inhibitor screening. |
Warning【警告】 | Toxicity: Standard Handling (A) |
Unit Definition【单位定义】 | One unit is defined as the amount of enyme that is required to deacetylate 1 pmol fluorescent HDAC peptide substrate per min at 30°C. |
Physical form【外形】 | 40 mM Tris-HCl pH8.0, 110mM NaCl, 2.2 mM KCl, 0.04% Tween 20, 3mM DTT, and 20% glycerol. |
Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-70°C). |
Other Notes【其他说明】 | Pandey, U.B., et al. 2007. Nature447, 859. Hubbert, C., et al. 2002. Nature417, 455. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |