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GST T2-2, Recombinant Human

产品编号:4145113
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4145113100 μG5520
产品别名

GST T2-2, Recombinant Human

glutathione S-transferase theta 2

基本信息
NACRES
NA.26
General description【一般描述】
Glutathione S-transferase theta 2 (GSTT2) is an enzyme that in humans is encoded by the GSTT2 gene. GSTT2 is mapped to human chromosome 22q11.2.
Biochem/physiol Actions【生化/生理作用】
The θ class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations.
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α, κ, μ, ω, π, σ, θ and ζ. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
human
recombinant【重组】
expressed in E. coli
Assay【测定】
>95% (SDS-PAGE)
form【形式】
frozen liquid
Specific Activity
12.6 units/mg protein (as assayed by the spectrophotometric determination of NADPH oxidation coupled to the glutathione peroxidase activity of GST T2-2 on cumene hydroperoxide (1.5 mM) in the presence of reduced glutathione (1 mM) in 100 mM NaPO4 (pH 7.0) at room temperature.)
mol wt【分子量】
25 kDa
concentration【浓度】
1.91 mg/mL
storage temp.【储存温度】
−70℃
Gene Information
human ... GSTT2(2953)
产品说明
Storage and Stability【储存及稳定性】
The enzyme should be used by the end-user customer within 1 year of receipt.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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