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GST S1-1, Recombinant Human
产品别名
GST S1-1, Recombinant Human
PGDS
hematopoietic prostaglandin D synthase
GSTS
PGD2
GSTS1
基本信息
NACRES | NA.26 |
Biochem/physiol Actions【生化/生理作用】 | Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Glutathione S-transferase sigma 1, also know as hematopoietic prostaglandin D synthase (HPGDS) is an enzyme that in humans is encoded by the HPGDS gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | human |
recombinant【重组】 | expressed in E. coli |
Assay【测定】 | >95% (SDS-PAGE) |
form【形式】 | frozen liquid |
Specific Activity | 24.07 (using spectrophotometric determination of 1-fluoro-2,4-dinitrobenzene (FDNB) conjugation with reduced glutathione (1 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.) |
mol wt【分子量】 | 23 kDa |
concentration【浓度】 | 0.9 mg/mL |
storage temp.【储存温度】 | −70℃ |
Gene Information | human ... HPGDS(27306) |
产品说明
Storage and Stability【储存及稳定性】 | The enzyme should be used by the end-user customer within 1 year of receipt. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |