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Complement C3a des-Arg, Human
| 产品编号： | 4144401 |
| 规格： | Complement C3a des-Arg, Human, is a single chain native des-Arg C3 complement component |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −70℃ |
| packaging【包装】 | 50 μg in Plastic ampoule Please refer to vial label for lot-specific concentration. |
基本信息
| General description【一般描述】 | Native, human des-Arg C3 complement component. Single chain, 76 amino acid peptide. Once the C3a peptide has been produced in human plasma or serum, it is rapidly converted to C3a des-Arg upon removal of the C-terminal arginine by endogenous serum carboxypeptidase N. This enzymatic process is considered to be a major mechanism for controlling C3a function in vivo because C3a des-Arg has <1% of the biological activity expressed by the C3a peptide. Therefore, C3a des-Arg can serve as a negative control molecule in experiments involved with the biological activities of the intact C3a anaphylatoxin peptide. |
| Biochem/physiol Actions【生化/生理作用】 | Ileum contraction assay: negative |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Physical form【外形】 | In PBS, pH 7.2. |
| Preparation Note【制备说明】 | Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-70°C). |
| Other Notes【其他说明】 | Kajita, T. and Hugli, T.E. 1991. Am. J. Pathol. 138, 1359. Bokish, V.A. and Muller-Eberhard, H.J. 1970. J. Clin. Invest.49, 2427. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
