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C5 Lenalidomide

产品编号:4144249
规格:≥95%
CAS NO:191732-70-4
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4144249100 MG3160
产品别名

191732-70-4

C5 Lenalidomide

Ligand for PROTAC research

E3 Ligase ligand

3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C13H13N3O3
Molecular weight
259.26
MDL number
MFCD31692701
Application【应用】
C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Other Notes【其他说明】
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC® Degraders for Targeted Protein Degradation

Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production

Targeted Protein Degradation by Small Molecules
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
Assay【测定】
≥95%
form【形式】
powder
storage temp.【储存温度】
2-8℃
SMILES string
NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1
NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1
安全信息
Pictograms【象形图】
GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H361d - H373
Precautionary Statements
P201 - P308 + P313
Hazard Classifications【危险分类】
Repr. 2 - STOT RE 2
Target Organs【靶器官】
Blood
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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