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3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid

产品编号:4143186
规格:analytical standard
CAS NO:86879-39-2
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
414318610 MG3670
414318650 MG12430
产品别名

86879-39-2

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid

CMPF

Propylurofuranic acid

3-Carboxy-4-methyl-5-propyl-2-furanpropionic acid

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C12H16O5
Molecular weight
240.25
MDL number
MFCD08436079
NACRES
NB.21
General description【一般描述】
3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a major metabolite of furan fatty acids, is a uremic toxin (UT), excreted into the urine via organic,anion transporters under physiological conditions. It is mostly reported to be accumulated in chronic kidney disease (CKD) patients. Monitoring of CMPF may be important to predict organic anion transporting polypeptide (OATP)1B activity in CKD patients as studies have implicated a decreased trend in (OATP)1B activity in patients with this uremic toxin. It is also found to be in increased concentrations, for patients who progress from prediabetes to type 2 diabetes, patients with renal failure, polyunsaturated fatty acids with high-temperature cooking and subjects who consume fish or fish oil.
Application【应用】
3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid may be used as an analytical reference standard for the quantification of the analyte in human plasma samples using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS).
产品性质
grade【等级】
analytical standard
Quality Level【质量水平】
100
Assay【测定】
≥95.0% (HPLC)
shelf life【保质期】
limited shelf life, expiry date on the label
application(s)
clinical testing
format【格式】
neat
storage temp.【储存温度】
2-8℃
SMILES string
OC(CCC1=C(C(O)=O)C(C)=C(CCC)O1)=O
InChI
1S/C12H16O5/c1-3-4-8-7(2)11(12(15)16)9(17-8)5-6-10(13)14/h3-6H2,1-2H3,(H,13,14)(H,15,16)
InChI key
WMCQWXZMVIETAO-UHFFFAOYSA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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