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2-Methylnicotinic acid imidazolide

产品编号:4143022
CAS NO:1055970-47-2
包装规格:50 MG,500 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
414302250 MG825
4143022500 MG2470
产品别名

1055970-47-2

2-Methylnicotinic acid imidazolide

1H-Imidazol-1-yl(2-methyl-3-pyridinyl)methanone

(1H-imidazol-1-yl)(2-methylpyridin-3-yl)methanone

RNA structure probe

mNAI

NAI

3-(1H-imidazole-1-carbonyl)-2-methylpyridine

RNA SHAPE probe

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C10H9N3O
Molecular weight
187.20
MDL number
MFCD25954959
Application【应用】
2-Methylnicotinic acid imidazolide (NAI or mNAI) is an RNA SHAPE probe for live-cell RNA structure profiling. SHAPE -- or selective 2′-hydroxyl acylation analyzed by primer extension -- uses small, electrophilic chemical probes to react with the 2′-hydroxyl group and provides insight to RNA structure and its dynamics in varied cells states or in cells with gene knockouts. It has also been extended to the SHALiPE approach, selective 2′-hydroxyl acylation with lithium ion-based primer extension.
Other Notes【其他说明】
Conditional control of RNA-guided nucleic acid cleavage and gene editing

Guidelines for SHAPE Reagent Choice and Detection Strategy for RNA Structure Probing Studies

SnapShot: RNA Structure Probing Technologies

Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA

Determination of in vivo RNA structure in low-abundance transcripts
产品性质
form【形式】
powder
Quality Level【质量水平】
100
mp
68-72 ℃
storage temp.【储存温度】
2-8℃
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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