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2-(Piperidin-4-yl)benzoic acid hydrochloride

产品编号:4142948
规格:95%
CAS NO:1955554-64-9
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4142948100 MG2220
产品别名

1955554-64-9

2-(Piperidin-4-yl)benzoic acid hydrochloride

Semi-flexible linker for PROTAC development

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C12H16ClNO2
Molecular weight
241.71
MDL number
MFCD08460728
Application【应用】
2-(Piperidin-4-yl)benzoic acid hydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
Other Notes【其他说明】
Portal: Building PROTAC® Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
Quality Level【质量水平】
100
Assay【测定】
95%
form【形式】
powder
storage temp.【储存温度】
2-8℃
SMILES string
O=C(C1=C(C2CCNCC2)C=CC=C1)O.Cl
O=C(C1=C(C2CCNCC2)C=CC=C1)O.Cl
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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