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Meloxicam-CAS 71125-38-7-Calbiochem
产品编号: | 4142285 |
规格: | A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC50 = 4.7 μM) relative to COX-1 (IC50 = 36.6 μM). |
CAS NO: | 71125-38-7 |
包装规格: | 100 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4142285 | 100 MG | 2820 |
产品别名
71125-38-7
Meloxicam-CAS 71125-38-7-Calbiochem
4-Hydroxy-2-methyl-N-(5-methyl-2-thiazoyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
基本信息
Empirical Formula【经验(实验)分子式】 | C14H13N3O4S2 |
Molecular weight | 351.40 |
General description【一般描述】 | A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC50 = 4.7 µM) relative to COX-1 (IC50 = 36.6 µM). Also inhibits the growth of colorectal cancer cells in vitro. A cell-permeable, non-steroidal, anti-inflammatory drug (NSAID) of the oxicam family that preferentially inhibits the inducible isoform of cyclooxygenase-2 (COX-2; IC50 = 4.7 µM) relative to cyclooxygenase-1 (COX-1; IC50 = 36.6 µM). Also inhibits the growth of colorectal cancer cells in vitro. |
Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Product does not compete with ATP. Reversible: no Target IC50: 4.7 µM, 36.6 µM against the inducible isoform of COX-2 relative to COX-1, respectively Primary Target COX-2 |
Warning【警告】 | Toxicity: Standard Handling (A) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C. |
Other Notes【其他说明】 | Blanco, F.J., et al. 1999. J. Rheumatol. 26, 1366. Davies, N.M., and Skjodt, N.M. 1999. Clin. Pharmacokinet. 36, 115. Goldman, A.P., et al. 1998. Carcinogenesis 19, 2195. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | off-white |
solubility【溶解性】 | DMSO: 10 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,19H,1-2H3,(H,15,16)/b13-11+ |
InChI key | DWMREKMVXIFPFM-ACCUITESSA-N |
packaging【包装】 | 100 mg in Plastic ampoule Packaged under inert gas |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P264 - P270 - P301 + P310 - P405 - P501 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 2 |