您的位置:首页 > 产品中心 > 99011-02-6, Imiquimod-CAS 99011-02-6-Calbiochem
Imiquimod-CAS 99011-02-6-Calbiochem
产品编号: | 4142263 |
规格: | An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. |
CAS NO: | 99011-02-6 |
包装规格: | 250 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4142263 | 250 MG | 3370 |
产品别名
99011-02-6
Imiquimod-CAS 99011-02-6-Calbiochem
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
基本信息
Empirical Formula【经验(实验)分子式】 | C14H16N4 |
Molecular weight | 240.30 |
MDL number | MFCD00866946 |
General description【一般描述】 | An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce the secretion of several pro-inflammatory cytokines and chemokines both in vitro and in vivo. |
Biochem/physiol Actions【生化/生理作用】 | Primary Target TLR7 (toll-like receptor 7) Product does not compete with ATP. Reversible: no Cell permeable: no |
Warning【警告】 | Toxicity: Toxic (F) |
Preparation Note【制备说明】 | warming to 60°C is required for complete solubilization. |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Upon thawing, warming may be required to resolubilize precipitated product. |
Other Notes【其他说明】 | Majewski, S., et al. 2005. Int. J. Dermatol.44, 14. Gibson, S.J., et al. 2002. Cell. Immunol.218, 74. Hemmi, H., et al. 2002. Nat. Immunol.3, 196. Megyeri, K., et al. 1995. Mol. Cell. Biol.15, 2207. Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | white |
solubility【溶解性】 | DMSO: 3 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17) |
InChI key | DOUYETYNHWVLEO-UHFFFAOYSA-N |
packaging【包装】 | 250 mg in Plastic ampoule Packaged under inert gas |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 - H315 - H319 |
Precautionary Statements | P264 - P270 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 |
Storage Class Code【储存分类代码】 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
WGK | WGK 3 |