广州伟伯科技有限公司
您的位置:首页 > 产品中心 > 219854-86-1, XIAP, GST tagged human
产品搜索:

XIAP, GST tagged human

产品编号:4141568
规格:recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
CAS NO:219854-86-1
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
414156850 μG6260
产品别名

219854-86-1

XIAP, GST tagged human

API3

ILP1

BIRC4

XLP2

MIHA

基本信息
NACRES
NA.32
General description【一般描述】
XIAP is a member of a family of proteins which inhibit apoptosis and act as mammalian cell-death suppressors. XIAP inhibits at least 2 members of the caspase family of cell-death proteases, caspase-3 and caspase-7. In addition, XIAP inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. Furthermore, XIAP can mediate protection of cells from apoptosis by utilizing both a JNK1 activation pathway that involves ILPIP and a caspase inhibition pathway that is independent of ILPIP. Disruption of the XIAP gene in human colon cancer cells can enhance sensitivity of these cells to exogenously added TRAIL suggesting that XIAP is a nonredundant modulator of TRAIL-mediated apoptosis.
Physical form【外形】
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note【制备说明】
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in baculovirus infected Sf9 cells
Assay【测定】
≥70% (SDS-PAGE)
form【形式】
buffered aqueous glycerol solution
mol wt【分子量】
~84 kDa
NCBI accession no.【NCBI登记号】
NM_001167
application(s)
cell analysis
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... XIAP(331)
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0093