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TNFSF8 human

产品编号:4141061
规格:recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
414106150 μG5480
产品别名

TNFSF8 human

Tumor necrosis factor ligand superfamily member 8

CD153

CD30L

CD30LG

基本信息
NACRES
NA.32
General description【一般描述】
TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. TNFSF8 was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin′s and some non-Hodgkin′s lymphomas. Recombinant human TNFSF8 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Physical form【外形】
0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 0.4 M Urea.
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in E. coli
Assay【测定】
≥80% (SDS-PAGE)
form【形式】
liquid
mol wt【分子量】
22 kDa (195 aa, 63-234 aa + His Tag)
packaging【包装】
pkg of 50 μg
concentration【浓度】
0.5 mg/mL
UniProt accession no.【UniProt登记号】
P32971 
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... TNFSF8(944)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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