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TAF1 (1371-1496) GST tag human

产品编号:4140843
规格:recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
包装规格:20 μG,100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
414084320 μG3560
4140843100 μG12110
产品别名

TAF1 (1371-1496) GST tag human

BA2R

TATA Box Binding Protein (TBP)-Associated Factor

CCGS

DYT3

NSCL2

TAFII250

XDP

TAF1 RNA Polymerase II

TAF2A

KAT4

CCG1

基本信息
NACRES
NA.32
General description【一般描述】
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. TAF1 is a component of transcription factor IID, and binds to core promoter sequences at the transcription start site. TAF1 helps control transcription by both its kinase and histone acetyltransferase enzymatic activities. It interacts with transcriptional activators such as the androgen receptor to promote transcription. Disruption of TAF1 causes dystonia 3 (X-linked torsion dystonia) and decreased apoptosis. This protein product contains the first bromodomain of TAF1.
Physical form【外形】
50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5 mM β-mercaptoethanol and 5% glycerol.
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in E. coli
Assay【测定】
≥95% (SDS-PAGE)
form【形式】
liquid
mol wt【分子量】
41.7 kDa (1371-1496 aa + NT GST Tag)
packaging【包装】
pkg of 100 μg
pkg of 20 μg
UniProt accession no.【UniProt登记号】
P21675
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... TAF1(6872)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H317 - H319 - H412
Precautionary Statements
P273 - P280 - P305 + P351 + P338 - P333 + P313 - P337 + P313
Hazard Classifications【危险分类】
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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