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Sphingosine kinase 2 Active from mouse
| 产品编号： | 4140713 |
| 规格： | recombinant, expressed in baculovirus, ≥70% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Sphingosine kinase 2 Active from mouse
SK2
SPK 2
SPHK2
基本信息
| NACRES | NA.54 |
| General description【一般描述】 | Mouse Sphingosine kinase 2 ( GenBank Accession No. NM_203280), full length with N-terminal His tag, MW = 68 kDa, expressed in a Baculovirus infected Sf9 cell expression system. |
| Application【应用】 | Sphingosine kinase 2 is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Sphingosine kinase 2 has been used in a study to assess blood–brain barrier protection in hypoxic preconditioning-induced cerebral ischemic tolerance. Sphingosine kinase 2 has also been used in a study to investigate sensitization of human colon cancer cells to sodium butyrate-induced apoptosis. |
| Unit Definition【单位定义】 | One unit of sphingosine kinase activity is defined as the amount of enzyme required to produce 1 pmol of S1P/min |
| Physical form【外形】 | Formulated in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol and 3 mM DTT. |
| Preparation Note【制备说明】 | Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70℃. Note: Enzyme is very sensitive to freeze/thaw cycles. |
产品性质
| recombinant【重组】 | expressed in baculovirus |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | aqueous solution |
| Specific Activity | ≥2 units/μg |
| mol wt【分子量】 | 68 kDa |
| NCBI accession no.【NCBI登记号】 | NM_203280 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | mouse ... SPHK2(56848) |
