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SPDP-dPEG®24-NHS ester

产品编号:4140683
包装规格:100 MG,1000 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4140683100 MG3070
41406831000 MG17410
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C63H113N3O29S2
Molecular weight
1440.70
MDL number
MFCD13185007
PubChem Substance ID【PubChem化学物质编号】
329823924
NACRES
NA.22
Features and Benefits【特点和优势】
SPDP-dPEG®24-NHS ester has an amine-reactive N-hydroxysuccinimide (NHS) ester at one end and a sulfhydryl-reactive 2-pyridyldithiol group at the opposite end. This has a single molecular weight PEG spacer arm, which confers greater water solubility to the crosslinker and linked proteins compared to crosslinkers having only hydrocarbon spacers. Protein aggregation and precipitation also are greatly reduced with SPDP-dPEG crosslinkers compared to crosslinkers that have only hydrocarbon spacers. dPEG spacer of specific length (97.3 Å) provides precise distance control between the SPDP moiety and the target molecule. Pyridyldithiol reagents produce disulfide-containing linkages that can be cleaved with reducing agents such as dithiothreitol (DTT). Crosslinking experiments with SPDP reagents are not limited to those involving proteins. Any of a variety of molecules with primary amines and sulfhydryl groups can be modified or crosslinked using SPDP reagents.
Legal Information【法律信息】
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
产品性质
Assay【测定】
>90%
form【形式】
solid or viscous liquid
reaction suitability
reagent type: cross-linking reagent
reactivity: amine reactive
reagent type: cross-linking reagent
reactivity: thiol reactive
polymer architecture【聚合物结构设计】
shape: linear
functionality: heterobifunctional
shipped in【运输】
ambient
storage temp.【储存温度】
−20℃
SMILES string
O=C(CCSSC1=NC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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