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RO5256390
产品别名
1043495-96-0
RO5256390
(S)-4-((S)-2-phenyl-butyl)-4,5-dihydro-oxazol-2-ylamine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H18N2O |
| Molecular weight | 218.29 |
| MDL number | MFCD28405494 |
| Biochem/physiol Actions【生化/生理作用】 | RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine′s reinforcng effects, and blocks binge-eating disorder. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D 14 to 19°, c = 1 in methanol |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC[C@@H](C[C@H]1COC(N)=N1)C2=CC=CC=C2 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
