RNA Polymerase II, p15.6 subunit, GST tagged human

NA.26

hRPB6 is a highly conserved subunit shared by all three RNA polymerases, consisting of 142 amino acid residues. The gene for yeast RPB6 is essential for cell viability and homologues of this subunit exist in archaeal and some viral RNA polymerases. For example the bacterial w (the fifth subunit of the bacterial RNAP core enzyme) and eukaryotic RPB6 are structural homologs. RPB6 has been shown to promote pol II complex assembly, and/or increase its stability, through specific interactions with the largest subunit of RNA pol II. In addition, RPB6 was found to make contact with three small subunits, RPB5, RPB7, and RPB8 and to play a role in the interaction between RNA polymerase II and the transcription elongation factor TFIIS.

Clear and colorless frozen liquid solution

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

human

expressed in E. coli

≥85% (SDS-PAGE)

frozen liquid

~40 kDa

pkg of 10 μg

avoid repeated freeze/thaw cycles

200 μg/mL

clear colorless

NM_021974

P61218

dry ice

−70℃

human ... POLR2F(5435)

10 - Combustible liquids

WGK 1