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RIZ1 (2-200) GST tag human
| 产品编号： | 4140382 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| 包装规格： | 50 μG，100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
RIZ1 (2-200) GST tag human
Retinoblastoma protein-interacting zinc finger protein
PR domain zinc finger protein 2
KMT8
PRDM2
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor suppressor that can arrest the cell cycle and induce apoptosis. RIZ2 however, is a proto-oncoprotein lacking the N-terminal PR domain containing the methyltransferase activity. When RIZ1 is silenced or mutated, the reduced methyltransferase activity can lead to inheritable changes in chromatin methylation and gene expression patterns. |
| Physical form【外形】 | 50 mM Tris, pH 7.5, containing 150 mM sodium chloride and 20% glycerol. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | liquid |
| mol wt【分子量】 | 49.5 kDa (2-200 aa + NT GST Tag) |
| packaging【包装】 | pkg of 100 μg pkg of 50 μg |
| UniProt accession no.【UniProt登记号】 | Q13029 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PRDM2(7799) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
