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NT-4 Protein, Human Recombinant Animal Free
| 产品编号： | 4139229 |
| 规格： | The Neurotrophin-4 protein (or NT-4 protein), also known as NT-5 protein, is a member of the NGF family of neuronal & epithelial growth factors. |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
NT-4 Protein, Human Recombinant Animal Free
NT4, Neurotrophin 4, Neurotrophin 4/5, NT4/5
基本信息
| eCl@ss | 32160405 |
| General description【一般描述】 | Neurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues). |
| Specificity【特异性】 | Cross Reactivty Mouse, Rat |
| Quality【质量】 | Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml. |
| Physical form【外形】 | Recombinant animal free human NT-4 is manufactured using all non-animal reagents |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | >98% (SDS-PAGE and HPLC) |
| impurities【杂质】 | <0.1 μg/mg protein endotoxin (<1EU/μg) |
| NCBI accession no.【NCBI登记号】 | NM_006179.3 |
| UniProt accession no.【UniProt登记号】 | P34130 |
| shipped in【运输】 | dry ice |
产品说明
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
