您的位置：首页 > 产品中心 > 152946-68-4， Nolatrexed dihydrochloride
Nolatrexed dihydrochloride
产品别名
152946-68-4
Nolatrexed dihydrochloride
AG 337
2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone dihydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H12N4OS · 2HCl |
| Molecular weight | 357.26 |
| MDL number | MFCD26960887 |
| Biochem/physiol Actions【生化/生理作用】 | Nolatrexed dihydrochloride is a water-soluble lipophilic quinazoline folate analog that exhibits potent antineoplastic activity. Nolatrexed is a potent thymidylate synthase inhibitor that inhibits thymine synthesis followed by inhibition of DNA replication. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC1=NC(C2=C(N1)C=CC(C)=C2SC3=CC=NC=C3)=O |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H341 - H361fd |
| Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Classifications【危险分类】 | Muta. 2 - Repr. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
