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奈达铂(Nedaplatin)

Nedaplatin
产品编号:4139080
CAS NO:95734-82-0
包装规格:50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
413908050 MG1710
产品别名

95734-82-0

奈达铂(Nedaplatin)

Nedaplatin

Cis-Diammine (Glycolato)Platinum

基本信息
Empirical Formula【经验(实验)分子式】
C2H8N2O3Pt
Molecular weight
303.17
Biochem/physiol Actions【生化/生理作用】
Nedaplatin is a second-generation cisplatin analog with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. Nedplatin is less nephrotoxic and neurotoxic compared to both cisplatin and carboplatin.
产品性质
form【形式】
powder
storage temp.【储存温度】
2-8℃
InChI
1S/C2H4O3.2H2N.Pt/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);2*1H2;/q;2*-1;+2
InChI key
KLNFSAOEKUDMFA-UHFFFAOYSA-N
安全信息
Pictograms【象形图】
GHS06,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H300 - H315 - H317 - H319 - H334 - H335 - H350
Precautionary Statements
P201 - P261 - P280 - P301 + P310 + P330 - P304 + P340 + P312 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1B - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
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