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Milli-Mark®Anti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4
产品编号: | 4120291 |
规格: | clone D5/16B4, Milli-Mark®, from mouse |
包装规格: | 100 TESTS |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Milli-Mark®Anti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4
58 kDa cytokeratin, epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types, keratin 5, keratin 5 (epidermolysis bullosa simplex,Dowling-Meara/Kobner/Weber-Cockayne types), keratin, type II cytoskeletal 5
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | The cytokeratins are a family of intermediate filaments found in almost all epithelial cells. They are divided into four subclasses depending on their patterns of reactivity and electrophoretic characteristics and are also arranged I a numbered series of 20 or more acoring to molecular weight and isoelectric point (Quinlan et al. 1985). Types 5 and 6 of cytokeratin (CK5/6) are in high frequency in mesothelial cells, as opposed to cells of adenocarcinoma. CK5/6 has been shown to be a reliable marker for mesothelioma and squamous cell carcinoma of the lung and Bowen′s disease. It does not react with pulmonary adenocarcinoma. |
Specificity【特异性】 | Antibody recognizes Human Cytokeratin. |
Immunogen【免疫原】 | Purified cytokeratin 5 (Wild, 1986) (Mischke, 1987). |
Application【应用】 | Research Category Cell Structure Research Sub Category Cytoskeleton Milli-MarkAnti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4 is an antibody against Cytokeratin 5 for use in FC. |
Quality【质量】 | Evaluated by flow cytometry using A431 cells |
Physical form【外形】 | Purified mouse monoclonal IgG1 conjugated to FITC in PBS buffer with 15mg/mL BSA and sodium azide at 0.1%. Protein A purified |
Analysis Note【分析说明】 | Control A431 cells |
Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | FITC conjugate |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | D5/16B4, monoclonal |
species reactivity | human |
manufacturer/tradename | Milli-Mark® |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_000415.2 |
UniProt accession no.【UniProt登记号】 | P13647 |
shipped in【运输】 | wet ice |
Gene Information | human ... KRT5(3852) |
产品说明
Target description【目标描述】 | The calculated for Cytokeratin is 62 kDa, however, different isoforms state Cytokeratin 4 (59 kDa), Cytokeratin 5 (58 kDa) and Cytokeratin 6 (56 kDa). |
Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |