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IL7Ra/CD127 human
产品编号: | 4119490 |
规格: | recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE) |
包装规格: | 10 μG,50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
NACRES | NA.32 |
General description【一般描述】 | Interleukin-7 receptor subunit α (IL7Ra) also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R. |
Physical form【外形】 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃. |
产品性质
biological source【生物来源】 | human |
recombinant【重组】 | expressed in HEK 293 cells |
Assay【测定】 | ≥95% (SDS-PAGE) |
form【形式】 | lyophilized |
mol wt【分子量】 | calculated mol wt 51 kDa (This protein is fused with Fc fragment of human IgG1 at the C-terminus.) observed mol wt 66-90 kDa (DTT-reduced. Protein migrates due to glycosylation. Glu 21 is the predicted N-terminal.) |
packaging【包装】 | pkg of 10 and 50 μg |
impurities【杂质】 | <1 EU/μg endotoxin (LAL test) |
UniProt accession no.【UniProt登记号】 | Q96F46 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... IL17Ra(23765) |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |