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Granzyme A human
| 产品编号： | 4119068 |
| 规格： | recombinant, expressed in mammalian cells, ≥95% (SDS-PAGE), ≥95% (HPLC) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Granzyme A human
Fragmentin-1
CTL tryptase
Cytotoxic T-lymphocyte proteinase 1
Granzyme-1
Hanukkah factor
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262). |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution of 20 mM MES and150 mM NaCl, pH 5.5. |
| Preparation Note【制备说明】 | Centrifuge the vial prior to opening. |
| Reconstitution【重悬】 | Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/mL.). This can further be diluted to other aqueous buffers. |
| Other Notes【其他说明】 | Recombinant Human Granzyme A is produced with mammalian cells expression system. Target protein is expressed with sequence (Glu27-Val262) of Human granzyme a (Uniprot #P12544) fused with a polyhistidine tag at the C-terminus. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in mammalian cells |
| Assay【测定】 | ≥95% (HPLC) ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | 26.9 kDa |
| packaging【包装】 | pkg of 10 μg |
| NCBI accession no.【NCBI登记号】 | P12544 |
| UniProt accession no.【UniProt登记号】 | P12544 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GZMA(3001) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
