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CD40L, Soluble human
| 产品编号： | 4117208 |
| 规格： | recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
CD40L, Soluble human
ADIPOQ-CD40L
ACRP30headless:TNFSF5
ACRP30headless:CD154
ACRP30headless:CD40L
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in CHO cells |
| tag【标签】 | FLAG® tagged |
| Assay【测定】 | >95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | 35-40 kDa by SDS-PAGE |
| packaging【包装】 | pkg of 10 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | <0.01 EU/μg endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | P29965 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CD40LG(959) |
基本信息
| General description【一般描述】 | CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form. |
| Biochem/physiol Actions【生化/生理作用】 | CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients. |
| Physical form【外形】 | Lyophilized from PBS |
| Reconstitution【重悬】 | Reconstitute with 100 μL deionized water. |
| Other Notes【其他说明】 | Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
| Legal Information【法律信息】 | FLAG is a registered trademark of sigma-aldrich Co. LLC |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
