BAZ2B (2064-2168) GST tag human

NA.32

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. BAZ2B is expressed in heart, skeletal, testis, and pancreatic tissues. A rare allele of BAZ2B has been identified to be a predictor of Sudden Cardiac Death.4 The full-length protein contains several DNA-targeting domains, including a methyl-CpG binding domain, a DNA-binding DDT domain, and a tandem PHD-bromodomain. This protein product contains the bromodomain of BAZ2B.

50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol.

human

expressed in E. coli

≥80% (SDS-PAGE)

liquid

40.2 kDa (2064-2168 aa + NT GST Tag)

pkg of 100 μg
pkg of 20 μg

Q9UIF8

dry ice

−70℃

human ... BAZ2B(29994)

GHS07

Warning

H317 - H319 - H412

P273 - P280 - P305 + P351 + P338 - P333 + P313 - P337 + P313

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

13 - Non Combustible Solids

WGK 3