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BAA473 (11-oxo-12S-hydroxy lithocholic acid methyl ester)
产品别名
27240-87-5
BAA473 (11-oxo-12S-hydroxy lithocholic acid methyl ester)
(3α,5β,12β)-3,12-dihydroxy-11-oxo-cholan-24-oic-acid methyl ester
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H40O5 |
| Molecular weight | 420.58 |
| General description【一般描述】 | BAA473 (11-oxo-12S-hydroxy lithocholic acid methyl ester) is a more potent analog of microbiome metabolite BAA485 (12-oxolithocholic acid) that activates the Pyrin inflammasome in myeloid and intestinal epithelial cells. BAA473 potently induces secretion of IL1β and IL18 in LPS-primed PBMCs and THP-1 cells. |
| Application【应用】 | Microbiome research, metabolomics research |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | chloroform: 20 mg/mL, colorless to light yellow |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
